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51.

155
Accesses

Research   Open Access

Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers

Albert Reece Immunity & Ageing 2007, 4:6 (24 September 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Blood samples from 'drug addicted' patients display altered profiles of common immune biomarkers of ageing compared to general medical patients, suggesting that the ageing process in drug addicts may follow a different time trajectory.

52.

152
Accesses

Research   Open Access

Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged

Lisa M Connor, Jacob E Kohlmeier, Lynn Ryan, Alan D Roberts, Tres Cookenham, Marcia A Blackman, David L Woodland Immunity & Ageing 2012, 9:28 (18 December 2012)

Abstract | Full text | PDF | PubMed

53.

153
Accesses

Review   Open Access

Aging, cancer, and cancer vaccines

Paolo Mazzola, Saba Radhi, Leonardo Mirandola, Giorgio Annoni, Marjorie Jenkins, Everardo Cobos, Maurizio Chiriva-Internati Immunity & Ageing 2012, 9:4 (17 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

54.

153
Accesses

Research   Open Access

Genetics of longevity. Data from the studies on Sicilian centenarians

Carmela R Balistreri, Giuseppina Candore, Giulia Accardi, Manuela Bova, Silvio Buffa, Matteo Bulati, Giusi I Forte, Florinda Listì, Adriana Martorana, Marisa Palmeri, MariaValeria Pellicanò, Loredana Vaccarino, Letizia Scola, Domenico Lio, Giuseppina Colonna-Romano Immunity & Ageing 2012, 9:8 (23 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

55.

152
Accesses

Research   Open Access

An investigation of the effects of the antioxidants, ebselen or N-acetyl cysteine on human peripheral blood mononuclear cells and T cells

Shiva Marthandan, Paul Hyland, Graham Pawelec, Yvonne Barnett Immunity & Ageing 2013, 10:7 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

56.

151
Accesses

Methodology   Open Access

Cytomegalovirus antibodies in dried blood spots: a minimally invasive method for assessing stress, immune function, and aging

Jennifer B Dowd, Allison E Aiello, Laura Chyu, Yuan-yen Huang, Thomas W McDade Immunity & Ageing 2011, 8:3 (13 January 2011)

Abstract | Full text | PDF | PubMed

57.

150
Accesses

Research   Open Access

Effect of ageing on CMV-specific CD8 T cells from CMV seropositive healthy donors

María Pita-Lopez, Inmaculada Gayoso, Olga DelaRosa, Javier G Casado, Corona Alonso, Elisa Muñoz-Gomariz, Raquel Tarazona, Rafael Solana Immunity & Ageing 2009, 6:11 (28 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

58.

150
Accesses

Commentary   Open Access

Report from the second cytomegalovirus and immunosenescence workshop

Mark Wills, Arne Akbar, Mark Beswick, Jos A Bosch, Calogero Caruso, Giuseppina Colonna-Romano, Ambarish Dutta, Claudio Franceschi, Tamas Fulop, Effrossyni Gkrania-Klotsas, Joerg Goronzy, Stephen J Griffiths, Sian M Henson, Dietmar Herndler-Brandstetter, Ann Hill, Florian Kern, Paul Klenerman, Derek Macallan, Richard Macaulay, Andrea B Maier, Gavin Mason, David Melzer, Matthew Morgan, Paul Moss, Janko Nikolich-Zugich, Annette Pachnio, Natalie Riddell, Ryan Roberts, Paolo Sansoni, Delphine Sauce, John Sinclair, Rafael Solana, Jan Strindhall, Piotr Trzonkowski, Rene van Lier, Rosanna Vescovini, George Wang, Rudi Westendorp, Graham Pawelec et al. Immunity & Ageing 2011, 8:10 (28 October 2011)

Abstract | Full text | PDF

59.

149
Accesses

Research   Open Access

Is the concentration of C-reactive protein in bacteraemia associated with age?

Astrid L Wester, Karl G Blaasaas, Torgeir Wyller Immunity & Ageing 2008, 5:8 (15 August 2008)

Abstract | Full text | PDF | PubMed

60.

145
Accesses

Research   Open Access

Immune correlates of aging in outdoor-housed captive rhesus macaques (Macaca mulatta)

Elizabeth S Didier, Chie Sugimoto, Lisa C Bowers, Imtiaz A Khan, Marcelo J Kuroda Immunity & Ageing 2012, 9:25 (14 November 2012)

Abstract | Full text | PDF | PubMed

61.

143
Accesses

Research   Open Access

Monocyte chemoattractant protein-1 promoter polymorphism and plasma levels in alzheimer’s disease

Elisa Porcellini, Manuela Ianni, Ilaria Carbone, Massimo Franceschi, Federico Licastro Immunity & Ageing 2013, 10:6 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

62.

144
Accesses

Research   Open Access

Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity

Andres Kriete, Kelli L Mayo, Nirupama Yalamanchili, William Beggs, Patrick Bender, Csaba Kari, Ulrich Rodeck Immunity & Ageing 2008, 5:5 (16 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

63.

144
Accesses

Hypothesis   Open Access

The discovery of how gender influences age immunological mechanisms in health and disease, and the identification of ageing gender-specific biomarkers, could lead to specifically tailored treatment and ultimately improve therapeutic success rates

Anna Maria Berghella, Ida Contasta, Tiziana Del Beato, Patrizia Pellegrini Immunity & Ageing 2012, 9:24 (13 November 2012)

Abstract | Full text | PDF | PubMed

64.

142
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Research   Open Access

Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity

Kris Kolibab, S Louise Smithson, Anne K Shriner, Sadik Khuder, Sandra Romero-Steiner, George M Carlone, MA Julie Westerink Immunity & Ageing 2005, 2:10 (27 June 2005)

Abstract | Full text | PDF | PubMed

65.

142
Accesses

Review   Open Access

The application of genetics approaches to the study of exceptional longevity in humans: potential and limitations

Anna Ferrario, Francesco Villa, Alberto Malovini, Fiorella Araniti, Annibale A Puca Immunity & Ageing 2012, 9:7 (23 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

66.

139
Accesses

Review   Open Access Highly Accessed

A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis

Sudhir Gupta, Anshu Agrawal, Sudhanshu Agrawal, Houfen Su, Sastry Gollapudi Immunity & Ageing 2006, 3:5 (19 May 2006)

Abstract | Full text | PDF | PubMed

67.

139
Accesses

Editorial   Open Access

“Positive biology”: the centenarian lesson

Calogero Caruso, Giuseppe Passarino, Annibale Puca, Giovanni Scapagnini Immunity & Ageing 2012, 9:5 (23 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

68.

138
Accesses

Research   Open Access

An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice

Anu Cherukuri, Kate L Stokes, Kathryn Patton, Howard Kuo, Kaori Sakamoto, Stacie Lambert, Elizabeth Stillman, Martin L Moore, Sujin Lee Immunity & Ageing 2012, 9:21 (2 October 2012)

Abstract | Full text | PDF | PubMed

69.

137
Accesses

Research   Open Access

Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Sudhir Gupta, Sudhanshu Agrawal, Sastry Gollapudi Immunity & Ageing 2013, 10:3 (23 January 2013)

Abstract | Full text | PDF | PubMed

70.

135
Accesses

Methodology   Open Access

Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes

Andrea Kunzmann, Dan Liu, Kathryn Annett, Muriel Malaisé, Bastian Thaa, Paul Hyland, Yvonne Barnett, Alexander Bürkle Immunity & Ageing 2006, 3:8 (19 July 2006)

Abstract | Full text | PDF | PubMed

71.

137
Accesses

Research   Open Access

Neutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects

Régine Minet-Quinard, M Chantal Farges, Emilie Thivat, Cécile Deleine, Gilles Mayot, Julius Brtko, Josep Ribalta, Brigitte Winklhofer-Roob, Edmond Rock, M Paule Vasson Immunity & Ageing 2010, 7:10 (20 August 2010)

Abstract | Full text | PDF | PubMed

72.

135
Accesses

Research   Open Access

Effects of life events and stress on neutrophil functions in elderly men

Kazumasa Tsukamoto, Kazuhiko Machida Immunity & Ageing 2012, 9:13 (9 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

73.

136
Accesses

Research   Open Access

Aging impacts isolated lymphoid follicle development and function

Keely G McDonald, Matthew R Leach, Conway Huang, Caihong Wang, Rodney D Newberry Immunity & Ageing 2011, 8:1 (7 January 2011)

Abstract | Full text | PDF | PubMed

74.

133
Accesses

Review   Open Access

Roy Walford and the immunologic theory of aging

Rita B Effros Immunity & Ageing 2005, 2:7 (25 April 2005)

Abstract | Full text | PDF | PubMed

75.

132
Accesses

Research   Open Access

Age matters:  Young T lymphocytes offer better protection from myeloma proliferation

Alexander F Glick, Yan S Song, Brian Hwang, John Lillvis, Pat Zanzonico, Camil Fuchs, Roger N Pearse, Paul Szabo, Marc E Weksler Immunity & Ageing 2013, 10:5 (18 February 2013)

Abstract | Full text | PDF | PubMed

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