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Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers
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Editor’s summary
Blood samples from 'drug addicted' patients display altered profiles of common immune biomarkers of ageing compared to general medical patients, suggesting that the ageing process in drug addicts may follow a different time trajectory.
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52.
152 Accesses
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Early dysregulation of the memory CD8+ T cell repertoire leads to compromised immune responses to secondary viral infection in the aged
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The discovery of how gender influences age immunological mechanisms in health and disease, and the identification of ageing gender-specific biomarkers, could lead to specifically tailored treatment and ultimately improve therapeutic success rates
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Immune response to pneumococcal polysaccharides 4 and 14 in elderly and young adults. I Antibody concentrations, avidity and functional activity
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An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice
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Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes
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Age matters: Young T lymphocytes offer better protection from myeloma proliferation
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