Additional file 3.

Correlation between T-lymphocyte subset and age. An increase in the ratios of central memory to naïve CD8⁺ (P = 0.0663) (A), effector memory to naïve CD8⁺ (P = 0.0527) (C), and central memory to naïve CD4⁺ (P = 0.0096) (E) with age is notable. The miR-92a level in CD8⁺ T-cells is negatively correlated with the ratio of central memory to naïve CD8⁺ cells (P = 0.0016) or effector memory/naïve CD8⁺ cells (P = 0.0073). By contrast, the miR-92a level in CD4⁺ T-cells is not correlated with the ratio of central memory to naïve CD4⁺ cells (P = 0.0925) (F).

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Ohyashiki et al. Immunity & Ageing 2011 8:11   doi:10.1186/1742-4933-8-11