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Open Access Commentary

Report from the second cytomegalovirus and immunosenescence workshop

Mark Wills1*, Arne Akbar2, Mark Beswick3, Jos A Bosch45, Calogero Caruso6, Giuseppina Colonna-Romano6, Ambarish Dutta7, Claudio Franceschi8, Tamas Fulop9, Effrossyni Gkrania-Klotsas10, Joerg Goronzy11, Stephen J Griffiths2, Sian M Henson2, Dietmar Herndler-Brandstetter12, Ann Hill13, Florian Kern14, Paul Klenerman15, Derek Macallan16, Richard Macaulay2, Andrea B Maier17, Gavin Mason1, David Melzer7, Matthew Morgan12, Paul Moss3, Janko Nikolich-Zugich18, Annette Pachnio3, Natalie Riddell2, Ryan Roberts1, Paolo Sansoni19, Delphine Sauce20, John Sinclair1, Rafael Solana21, Jan Strindhall22, Piotr Trzonkowski23, Rene van Lier24, Rosanna Vescovini19, George Wang25, Rudi Westendorp26 and Graham Pawelec27

Author Affiliations

1 Department of Medicine, University of Cambridge, Cambridge, UK

2 Division of Infection and Immunity, University College London, London, UK

3 School of Cancer Sciences, University of Birmingham, Birmingham, UK

4 College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK

5 Mannheim Institute of Public Health, Social and Preventive Medicine, University of Heidelberg, Mannheim, Germany

6 Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Palermo, Italy

7 Epidemiology and Public Health Group, Peninsula Medical School, University of Exeter, Exeter, UK

8 Dept. Experimental Pathology, University of Bologna, Bologna, Italy

9 Research Centre on Aging, Immunology Program, Geriatric Division, Faculty of Medicine, University of Sherbrooke, Sherbrooke, Canada

10 Addenbrooke's Hospital, Cambridge, UK

11 Stanford University School of Medicine, Stanford, CA, USA

12 School of Immunity and Infection, University of Birmingham, Birmingham, UK

13 Dept Microbiology and Immunology, Oregon Health and Science University, Portland, OR, USA

14 BSMS, University of Sussex Campus, Falmer, UK

15 NIHR Biomedical Research Centre, Nuffield Dept of Clinical Medicine, University of Oxford, Oxford, UK

16 Centre for Infection, St George's, University of London, Cranmer Terrace, London, UK

17 Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

18 Department of Immunobiology and the Arizona Center on Aging, University of Arizona, Tucson, AZ, USA

19 Department of Internal Medicine and Biomedical Sciences, University of Parma, Parma, Italy

20 INSERM, Infections and Immunity, Universite Pierre et Marie Curie-Paris, Paris, France

21 Instituto Maimonides de Investigación Biomédica de Cordoba (IMIBIC), Hospital Universitario Reina Sofía, Universidad de Cordoba, Cordoba, Spain

22 Department of Natural Science and Biomedicine, School of Health Sciences, Jönköping University, Jönköping, Sweden

23 Department of Clinical Immunology and Transplantology, Medical University of Gdańsk, Gdańsk, Poland

24 Sanquin Blood Supply Foundation and Department of Experimental Immunology, Amsterdam, The Netherlands

25 Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

26 Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands

27 Department of Internal Medicine II, University of Tübingen, Tübingen, Germany

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Immunity & Ageing 2011, 8:10  doi:10.1186/1742-4933-8-10

Published: 28 October 2011

Abstract

The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory frequency, inflation and immunosenescence; cytomegalovirus in aging, mortality and disease states; and the immunobiology of cytomegalovirus-specific T cells and effects of the virus on vaccination. This commentary summarizes the major findings of these presentations and references subsequently published work from the presenter laboratory where appropriate and draws together major themes that were subsequently discussed along with new areas of interest that were highlighted by this discussion.