|
Sensitivity of a "high" concentration of C-reactive protein (CRP) as indicator of bacteraemia by gender, species, and age |
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| Sex |
Species |
Age group |
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| Female |
Male |
S. pneumoniae |
E. coli |
16–64 |
65–84 |
≥ 85 |
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|
|
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| Cut-off (CRP) 40 mg/L |
Sensitivity (%) |
90.2 |
88.2 |
92.6 |
88.0 |
90.4 |
88.5 |
90.5 |
| 95% CI |
87.6 – 92.8 |
85.0 – 91.4 |
89.4 – 95.8 |
85.5 – 90.5 |
86.6 – 93.4 |
85.5 – 91.5 |
85.8 – 95.2 |
|
| p-value |
0.339 |
0.046 |
0.714 |
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| Cut-off (CRP) 80 mg/L |
Sensitivity (%) |
81.4 |
75.6 |
89.1 |
74.8 |
82.0 |
75.6 |
82.3 |
| 95% CI |
78.0 – 84.8 |
71.3 – 79.9 |
84.8 – 93.4 |
71.4 – 78.2 |
77.7 – 86.3 |
71.6 – 79.6 |
76.1 – 88.5 |
|
| p-value |
0.037 |
< 0.01 |
0.060 |
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| Cut-off (CRP) 120 mg/L |
Sensitivity (%) |
69.7 |
64.6 |
82.4 |
61.5 |
71.7 |
64.8 |
67.3 |
| 95% CI |
65.7 – 73.7 |
59.9 – 69.3 |
77.7 – 87.1 |
57.7 – 65.3 |
66.7 – 76.8 |
60.4 – 69.2 |
59.7 – 74.9 |
|
| p-value |
0.106 |
< 0.01 |
0.145 |
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|
CI = confidence interval, p-values for between-group comparison of sensitivity (chi-square test) | ||||||||
Wester et al. Immunity & Ageing 2008 5:8 doi:10.1186/1742-4933-5-8 |
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