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List of inflammatory genes. Given are accession numbers of genes, fold changes and p-values between the group of older and young donors, a Pearson correlation coefficient (R) expressing similarity to the NF-κB profile as seen in Figure 1, and a description of genes. |
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| Accession ID |
Fold |
p |
R |
Description |
|
|
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| NM_001733 |
2.3 |
0.023 |
0.74 |
complement component 1, r subcomponent (C1R) |
| NM_005438 |
2.0 |
0.033 |
0.71 |
FOS-like antigen 1 (FOSL1) |
| NM_000732 |
2.0 |
0.012 |
0.69 |
CD3D antigen, delta polypeptide (TiT3 complex) (CD3D) |
| NM_000586 |
4.6 |
0.020 |
0.68 |
interleukin 2 (IL2) |
| NM_004591 |
2.0 |
0.068 |
0.65 |
chemokine (C-C motif) ligand 20 (CCL20) |
| NM_005218 |
2.1 |
0.066 |
0.61 |
defensin, beta 1 (DEFB1) |
| NM_002993 |
2.0 |
0.097 |
0.58 |
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (CXCL6) |
| NM_003034 |
2.8 |
0.040 |
0.58 |
sialyltransferase 8A (GD3 synthase) (SIAT8A) |
| NM_002127 |
3.5 |
0.104 |
0.56 |
HLA-G histocompatibility antigen, class I, G (HLA-G) |
| NM_006644 |
2.6 |
0.102 |
0.52 |
heat shock 105 kDa/110 kDa protein 1 (HSPH1) |
| NM_080741 |
6.1 |
0.093 |
0.49 |
sialidase 4 (NEU4) |
| NM_002089 |
2.4 |
0.020 |
0.46 |
chemokine (C-X-C motif) ligand 2 (CXCL2) |
| NM_001928 |
5.6 |
0.094 |
0.45 |
D component of complement (adipsin) (DF) |
| NM_001937 |
2.2 |
0.017 |
0.41 |
dermatopontin (DPT) |
| NM_000634 |
4.3 |
0.068 |
0.39 |
interleukin 8 receptor, alpha (IL8RA) |
| NM_004887 |
3.5 |
0.047 |
0.38 |
chemokine (C-X-C motif) ligand 14 (CXCL14) |
| NM_024298 |
6.8 |
0.023 |
0.30 |
leukocyte receptor cluster (LRC) member 4 (LENG4) |
| NM_002416 |
3.6 |
0.068 |
0.22 |
chemokine (C-X-C motif) ligand 9 (CXCL9) |
| NM_006573 |
3.3 |
0.040 |
0.17 |
tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B) |
| NM_000575 |
2.7 |
0.033 |
0.17 |
interleukin 1, alpha (IL1A) |
| NM_003641 |
2.0 |
0.088 |
0.13 |
interferon induced transmembrane protein 1 (9–27) (IFITM1) |
| NM_000888 |
3.2 |
0.042 |
0.09 |
integrin, beta 6 (ITGB6) |
| NM_005521 |
2.0 |
0.094 |
0.06 |
T-cell leukemia, homeobox 1 (TLX1) |
| NM_004031 |
2.0 |
0.064 |
0.05 |
interferon regulatory factor 7 (IRF7), transcript variant d |
| NM_000716 |
2.2 |
0.085 |
0.05 |
complement component 4 binding protein, beta (C4BPB) |
| NM_007112 |
4.7 |
0.073 |
0.04 |
thrombospondin 3 (THBS3) |
| NM_182764 |
3.4 |
0.061 |
0.04 |
engulfment and cell motility 2 (ELMO2), transcript variant 3 |
| NM_207517 |
2.7 |
0.041 |
0.01 |
ADAMTS-like 3 (ADAMTSL3) |
| NM_148962 |
4.8 |
0.083 |
-0.03 |
oxoeicosanoid (OXE) receptor 1 (OXER1) |
| NM_002427 |
5.1 |
0.093 |
-0.11 |
matrix metalloproteinase 13 (collagenase 3) (MMP13) |
| NM_000570 |
3.3 |
0.094 |
-0.15 |
Fc fragment of IgG, low affinity IIIb, receptor for (CD16) (FCGR3B) |
| NM_000577 |
2.7 |
0.116 |
-0.19 |
interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
| NM_000603 |
2.4 |
0.088 |
-0.21 |
nitric oxide synthase 3 (endothelial cell) (NOS3) |
| NM_002177 |
2.3 |
0.127 |
-0.33 |
interferon, omega 1 (IFNW1) |
Kriete et al. Immunity & Ageing 2008 5:5 doi:10.1186/1742-4933-5-5 |
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