Table 4

Correlation analysis between ROS production and inflammatory markers.


Neutrophil counts
Spontaneous ROS production



Old
Young
Old
Young

IL-8
-0.22
0.70 *
0.00
0.44
MCP-1
-0.10
0.44
-0.28
0.14
TNF-α
0.37 *
0.02
0.29
0.49
IL-6
0.48 **
0.27
0.13
0.35
CRP
0.44 *
-0.07
0.13
0.36
SAA
0.47 **
-0.18
-0.13
0.22
HSP70
0.00
0.47
-0.41 *
0.12

Median channel of
fMLP-stimulated ROS production
LPS-stimulated ROS production


Old
Young
Old
Young

IL-8
0.36
0.00
-0.15
0.31
MCP-1
-0.18
0.16
0.00
0.41
TNF-α
0.36
0.11
-0.28
-0.04
IL-6
0.34
0.09
0.18
0.32
CRP
0.23
0.28
-0.08
0.16
SAA
0.29
0.49
-0.29
0.34
HSP70
-0.04
0.12
0.14
0.40

*; P < 0.05, **; P < 0.01, statistically significant correlation coefficient by Spearman.

Ogawa et al. Immunity & Ageing 2008 5:13   doi:10.1186/1742-4933-5-13