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Immunopathogenesis of primary biliary cirrhosis: an old wives' tale
Daniel S Smyk, Eirini I Rigopoulou, Ana Lleo, Robin D Abeles, Athanasios Mavropoulos, Charalambos Billinis, Pietro Invernizzi, Dimitrios P Bogdanos Immunity & Ageing 2011, 8:12 (2 December 2011)
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Age-related decrease of miRNA-92a levels in human CD8+ T-cells correlates with a reduction of naïve T lymphocytes
Michiyo Ohyashiki, Junko H Ohyashiki, Ayako Hirota, Chiaki Kobayashi, Kazuma Ohyashiki Immunity & Ageing 2011, 8:11 (15 November 2011)
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Report from the second cytomegalovirus and immunosenescence workshop
Mark Wills, Arne Akbar, Mark Beswick, Jos A Bosch, Calogero Caruso, Giuseppina Colonna-Romano, Ambarish Dutta, Claudio Franceschi, Tamas Fulop, Effrossyni Gkrania-Klotsas, Joerg Goronzy, Stephen J Griffiths, Sian M Henson, Dietmar Herndler-Brandstetter, Ann Hill, Florian Kern, Paul Klenerman, Derek Macallan, Richard Macaulay, Andrea B Maier, Gavin Mason, David Melzer, Matthew Morgan, Paul Moss, Janko Nikolich-Zugich, Annette Pachnio, Natalie Riddell, Ryan Roberts, Paolo Sansoni, Delphine Sauce, John Sinclair, Rafael Solana, Jan Strindhall, Piotr Trzonkowski, Rene van Lier, Rosanna Vescovini, George Wang, Rudi Westendorp, Graham Pawelec et al.
Immunity & Ageing 2011, 8:10 (28 October 2011)
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Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cells
Saara Marttila, Juulia Jylhävä, Carita Eklund, Antti Hervonen, Marja Jylhä, Mikko Hurme Immunity & Ageing 2011, 8:9 (11 October 2011)
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Immune risk phenotype is associated with nosocomial lung infections in elderly in-patients
A Plonquet, S Bastuji-Garin, F Tahmasebi, C Brisacier, K Ledudal, JP Farcet, E Paillaud Immunity & Ageing 2011, 8:8 (1 October 2011)
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Editor’s summary
Elderly patients who contract in-hospital infections exhibit altered immune parameters (e.g high memory T Cells) compared to those without infection, which should be taken into consideration when developing care plans.
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The "Alzheimer's disease signature": potential perspectives for novel biomarkers
Sergio Davinelli, Mariano Intrieri, Claudio Russo, Alfonso Di Costanzo, Davide Zella, Paolo Bosco, Giovanni Scapagnini Immunity & Ageing 2011, 8:7 (20 September 2011)
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Editor’s summary
Davinelli et al. review potential biomarker candidates from the latest research, which could hold the key to the Alzheimer's disease signature, providing a way of diagnosing the disease and its progressive stages.
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Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors
Jessica B Lee, Mathias Oelke, Lakshmi Ramachandra, David H Canaday, Jonathan P Schneck Immunity & Ageing 2011, 8:6 (16 August 2011)
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Identification of serum biomarkers for aging and anabolic response
Camellia Banerjee, Jagadish Ulloor, Edgar L Dillon, Qusai Dahodwala, Brittani Franklin, Thomas Storer, Paola Sebastiani, Melinda Sheffield-Moore, Randall J Urban, Shalender Bhasin, Monty Montano Immunity & Ageing 2011, 8:5 (20 June 2011)
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Editor’s summary
Testosterone supplements have been shown to affect levels of certain ageing biomarkers, providing a potential gauge to trace the response to these therapeutic supplements in elderly patients aiming to improve muscle mass.
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Inflammatory and Immunological parameters in adults with Down syndrome
Maria BF Trotta, João B Serro Azul, Mauricio Wajngarten, Simone G Fonseca, Anna C Goldberg, Jorge E Kalil Immunity & Ageing 2011, 8:4 (16 April 2011)
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Cytomegalovirus antibodies in dried blood spots: a minimally invasive method for assessing stress, immune function, and aging
Jennifer B Dowd, Allison E Aiello, Laura Chyu, Yuan-yen Huang, Thomas W McDade Immunity & Ageing 2011, 8:3 (13 January 2011)
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Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets
Nicolle HR Litjens, Elly A de Wit, Michiel GH Betjes Immunity & Ageing 2011, 8:2 (8 January 2011)
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Aging impacts isolated lymphoid follicle development and function
Keely G McDonald, Matthew R Leach, Conway Huang, Caihong Wang, Rodney D Newberry Immunity & Ageing 2011, 8:1 (7 January 2011)
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Alzheimer's disease gene signature says: beware of brain viral infections
Elisa Porcellini, Ilaria Carbone, Manuela Ianni, Federico Licastro Immunity & Ageing 2010, 7:16 (14 December 2010)
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Editor’s summary
Porcellini et al. present the hypothesis that genetic susceptibility to pathogenic infection of the brain may, in turn, influence the risk of neurodegeneration and AD in later life.
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Immune response of macrophages from young and aged mice to the oral pathogenic bacterium Porphyromonas gingivalis
Yazdani B Shaik-Dasthagirisaheb, Alpdogan Kantarci, Frank C Gibson Immunity & Ageing 2010, 7:15 (29 November 2010)
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Age related changes in T cell mediated immune response and effector memory to Respiratory Syncytial Virus (RSV) in healthy subjects
Maria Cusi, Barbara Martorelli, Giuseppa Di Genova, Chiara Terrosi, Giuseppe Campoccia, Pierpaolo Correale Immunity & Ageing 2010, 7:14 (20 October 2010)
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Immunosenescence and Cytomegalovirus: where do we stand after a decade?
Graham Pawelec, Arne Akbar, Peter Beverley, Calogero Caruso, Evelyna Derhovanessian, Tamas Fülöp, Paul Griffiths, Beatrix Grubeck-Loebenstein, Klaus Hamprecht, Gerhard Jahn, Florian Kern, Sven D Koch, Anis Larbi, Andrea B Maier, Derek Macallan, Paul Moss, Sandrine Samson, Jan Strindhall, Emanuelle Trannoy, Mark Wills Immunity & Ageing 2010, 7:13 (7 September 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Effectiveness of BCG vaccination to aged mice
Tsukasa Ito, Takemasa Takii, Mitsuo Maruyama, Daisuke Hayashi, Takeshi Wako, Azusa Asai, Yasuhiro Horita, Keiichi Taniguchi, Ikuya Yano, Saburo Yamamoto, Kikuo Onozaki Immunity & Ageing 2010, 7:12 (1 September 2010)
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Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial
Yoshifumi Kotani, Shoji Shinkai, Hiroshi Okamatsu, Masamichi Toba, Kishiko Ogawa, Hiroto Yoshida, Taro Fukaya, Yoshinori Fujiwara, Paulo HM Chaves, Keiji Kakumoto, Noriyuki Kohda Immunity & Ageing 2010, 7:11 (26 August 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Neutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects
Régine Minet-Quinard, M Chantal Farges, Emilie Thivat, Cécile Deleine, Gilles Mayot, Julius Brtko, Josep Ribalta, Brigitte Winklhofer-Roob, Edmond Rock, M Paule Vasson Immunity & Ageing 2010, 7:10 (20 August 2010)
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Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases
Thi Vo, Patrice Godard, Marie de Saint-Hubert, Gabriel Morrhaye, Christian Swine, Vincent Geenen, Henri J Martens, Florence Debacq-Chainiaux, Olivier Toussaint Immunity & Ageing 2010, 7:9 (17 August 2010)
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Characterization of leukotrienes in a pilot study of older asthma subjects
Sharmilee M Nyenhuis, Elizabeth A Schwantes, Sameer K Mathur Immunity & Ageing 2010, 7:8 (5 July 2010)
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Factors that may impact on immunosenescence: an appraisal
Joseph Ongrádi, Valéria Kövesdi Immunity & Ageing 2010, 7:7 (14 June 2010)
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BELFAST nonagenarians: nature or nurture? Immunological, cardiovascular and genetic factors
I M Rea Immunity & Ageing 2010, 7:6 (27 May 2010)
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Age-related differences in integrin expression in peripheral blood lymphocytes
Christine V Crooks, Martin L Cross, Clare R Wall Immunity & Ageing 2010, 7:5 (26 April 2010)
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The effect of ageing on human lymphocyte subsets: comparison of males and females
Jun Yan, Judith M Greer, Renee Hull, John D O'Sullivan, Robert D Henderson, Stephen J Read, Pamela A McCombe Immunity & Ageing 2010, 7:4 (16 March 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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